Wednesday 27 February 2013

'Justified': Major Death Seems To Have Little Impact On Raylan Givens (VIDEO)

  • "666 Park Avenue"

    <strong>"666 Park Ave.," ABC</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: <a href="http://www.huffingtonpost.com/2012/11/16/666-park-avenue-canceled_n_2147290.html">ABC pulled the plug</a> on this supernatural drama earlier in the season.

  • "The Bachelor"

    <strong>"The Bachelor," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: While ratings may have dropped, "The Bachelor" will likely see another season on ABC as tabloids and viewers still care about the comings and goings of contestants.

  • "Body of Proof"

    <strong>"Body of Proof," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: ABC is keen on this Dana Delany drama, but the ratings for this upcoming third season will be the true test.

  • "Castle"

    <strong>"Castle," ABC</strong> <strong>Status</strong>: Likely to be renewed. <strong>Why</strong>: Strong ratings and a dedicated viewership will keep "Castle" on the schedule.

  • "Dancing With the Stars"

    <strong>"Dancing With the Stars," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: The series is hurting in the ratings ... by "DWTS" standards. It's still a strong player for ABC, but the new season hasn't premiered yet.

  • "Don't Trust The B---- In Apt. 23"

    <strong>"Don't Trust The B---- In Apt. 23," ABC</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: <a href="http://www.huffingtonpost.com/2013/01/22/apartment-23-canceled-dont-trust-the-b_n_2528858.html">ABC pulled the low-rated comedy</a> from it schedule and the stars took to Twitter to announce the cancellation.

  • "Family Tools"

    <strong>"Family Tools," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: This ABC comedy has yet to debut, but a May 1 premiere date doesn't look great.

  • "Grey's Anatomy"

    <strong>"Grey's Anatomy," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: America still loves McDreamy and the goings on at Seattle Grace. Expect "Grey's" to return.

  • "Happy Endings"

    <strong>"Happy Endings," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: Always the bubble show, never the surefire renewal hit. "Happy Endings" has suffered from many ratings ailments, including bad scheduling (<a href="http://www.huffingtonpost.com/2013/02/14/happy-endings-friday-abc_n_2683091.html">it's moving to Friday night</a>) and lack of promo. But this ahmahzing show has some serious fans that could keep it afloat for another season ... maybe on another network (a la "Cougar Town.")

  • "How To Live With Your Parents (For The Rest Of Your Life)"

    <strong>"How To Live With Your Parents (For The Rest Of Your Life)," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: The ABC comedy starring Sarah Chalke has yet to debut, but its late season bow doesn't exactly bode well for its future.

  • "Last Man Standing"

    <strong>"Last Man Standing," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Viewers still love Tim Allen! Paired with "Malibu Country," "Last Man Standing" has been performing well on Friday nights and <a href="http://www.huffingtonpost.com/2013/02/14/jonathan-taylor-thomas-last-man-standing-home-improvement_n_2686307.html">will soon see Allen's "Home Improvement" co-star Jonathan Tyler Thomas</a>.

  • "Last Resort"

    <strong>"Last Resort," ABC</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: <a href="http://www.huffingtonpost.com/2012/11/16/last-resort-canceled-abc_n_2147316.html">ABC killed the Shawn Ryan drama</a> in late 2012.

  • "Malibu Country"

    <strong>"Malibu Country," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: "Malibu Country" has been performing well on Friday nights. Lesson: Never underestimate the star power of Reba.

  • "The Middle"

    <strong>"The Middle," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Now in its fourth season, "The Middle" is still pulling in more than 8 million viewers an episode as the anchor of ABC's Wednesday comedies.

  • "Mistresses"

    <strong>"Mistresses," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: ABC sent out the pilot with its 2012-2013 offerings, but the drama, which is based on the UK series of the same name, has yet to premiere despite having Alyssa Milano and "Lost" alum Yunjin Kim.

  • "Modern Family"

    <strong>"Modern Family," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: A fan favorite and Emmy darling, "Modern Family" will be back and will make ABC lots of money in syndication.

  • "Nashville"

    <strong>"Nashville," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: Critical acclaim doesn't always equate to rating success. The show has stabilized in Nielsen ratings, but its future really depends on the strength of ABC's drama pilots.

  • "The Neighbors"

    <strong>"The Neighbors," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: One of the few "hits" of the season, "The Neighbors" has found an audience and kept it pretty steadily week after week (<a href="http://www.huffingtonpost.com/2012/06/11/abc-shows-fall-tv-2012-2013_n_1581796.html">much to our dismay</a>).

  • "Once Upon a Time"

    <strong>"Once Upon a Time," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: A ratings hit in its second season, "Once Upon a Time" is almost sure to be back for a third season full of fairytale adventures.

  • "Private Practice"

    <strong>"Private Practice," ABC</strong> <strong>Status</strong>: Ended <strong>Why</strong>: The "Grey's Anatomy" spinoff said goodbye in January 2013.

  • "Red Widow"

    <strong>"Red Widow," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: The show has a late February debut on ABC.

  • "Revenge"

    <strong>"Revenge," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: "Revenge" has fallen out of critical favor and seen lower ratings in its new Sunday night home. But none of ABC's freshman dramas are doing well, so that works in the show's favor.

  • "Rookie Blue"

    <strong>"Rookie Blue," ABC</strong> <strong>Status</strong>: Renewed <strong>Why</strong>: The Canadian co-production will return for a fourth season on ABC during the summer of 2013.

  • "Scandal"

    <strong>"Scandal," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Shonda Rhimes has another hit on her hands. Now in its second season, "Scandal" has benefited from word-of-mouth and has been rising in the ratings (even recently beating out its lead in "Grey's Anatomy"). A likable star -- Kerry Washington -- and continued buzz will keep "Scandal" on the schedule.

  • "Suburgatory"

    <strong>"Suburgatory," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: The series started Season 2 off strong in the ratings, but its audience has slowly eroded. Its not the worst-performing ABC sitcom, but its buzziness has died down as well.

  • "Zero Hour"

    <strong>"Zero Hour," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: The Anthony Edwards vehicle debuted to 6.3 million viewers with a 1.3 rating in the key 18-49 demographic, making it <a href="http://www.huffingtonpost.com/2013/02/15/zero-hour-ratings_n_2695800.html">the least-watched premiere for a scripted series in ABC's history</a>. Obviously, things aren't looking good for the "ER" star's comeback, but maybe the ratings will improve.

  • "2 Broke Girls"

    <strong>"2 Broke Girls," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: It's not doing "The Big Bang Theory" numbers, but "2 Broke Girls" has maintained a viewership over its two seasons.

  • "The Amazing Race"

    <strong>"The Amazing Race," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: As an Emmy and fan favorite, "The Amazing Race" has been a strong player for CBS.

  • "The Big Bang Theory"

    <strong>"The Big Bang Theory," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Now in its sixth season, "Big Bang" is reaching series-high ratings. Even up against reality powerhouse "American Idol," "The Big Bang Theory" has been delivering with crazy high numbers in the 18-49 demographic, beating out what was once Fox's juggernaut.

  • "Blue Bloods"

    <strong>"Blue Bloods," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: The Tom Selleck-fronted police drama is a strong ratings performer for CBS on Fridays. It will likely be back to help launch new Friday shows and produce enough episodes to enter syndication.

  • "Criminal Minds"

    <strong>"Criminal Minds," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: As one of CBS's strong procedural players, the series has been steady in the ratings and will likely be renewed to help anchor a night and launch a new drama.

  • "CSI"

    <strong>"CSI," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Of the two "CSI" shows on the air, "CSI" is the stronger player in the TV landscape. The show is nowhere near its earlier ratings, but after such a successful run, CBS would be smart to bring the show -- and some old faces back -- for an abbreviated farewell season.

  • "CSI: NY"

    <strong>"CSI: NY," CBS</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: The spinoff series will be entering Season 10 in the 2013-2014 season. The ratings have faded over the years, but they're still pretty stable, especially for Fridays. It's a toss up, depending on how well CBS's development slate goes.

  • "Elementary"

    <strong>"Elementary," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: One of the very few freshman series hits during the 2012-2013 TV season, CBS is very keen on this modern-day take on Sherlock Holmes. The audience has been steady and the network even gave it the post-Super Bowl timeslot.

  • "Golden Boy"

    <strong>"Golden Boy," CBS</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: CBS certainly has a handsome star at the front of this cop drama, but its late season entry and Friday timeslot could be a hint toward CBS's confidence in the show.

  • "The Good Wife"

    <strong>"The Good Wife," CBS</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: A former ratings champ, "The Good Wife" has slipped to series low ratings on Sunday nights. Blame football overrun, fan-detested storylines or too many guest stars, but "The Good Wife" is certainly in the danger zone. What it has going for it: star power and critical praise, plus its nearing a good syndication sweet spot.

  • "Hawaii Five-0"

    <strong>"Hawaii Five-0," CBS</strong <strong>Status</strong>: On the bubble <strong>Why</strong>: Its ratings -- bouncing around 8-10 million viewers an episode, are great ... if you're a show on NBC. By CBS standards, they're kind of meh, but this show has stars with very active fan followings. CBS could axe the drama to make room for new procedurals, or stick with it to get the show close to syndication gold.

  • "How I Met Your Mother"

    <strong>"How I Met Your Mother," CBS</strong> <strong>Status</strong>: Renewed <strong>Why</strong>: CBS handed out a ninth and final season to this comedy with the entire cast returning. Expect to meet the mother, finally.

  • "Made In Jersey"

    <strong>"Made In Jersey," CBS</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: CBS pulled the plug on this legal drama very early on in the season because of low ratings.

  • "The Mentalist"

    <strong>"The Mentalist," CBS</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: "The Mentalist" has fallen to mediocre ratings -- by CBS standards -- and could be axed in favor of making room for a new drama.

  • "Mike & Molly"

    <strong>"Mike & Molly," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: The ratings are down a little bit from last year, but Melissa McCarthy's star continues to rise. CBS will likely bring the show back for another season.

  • "NCIS"

    <strong>"NCIS," CBS</strong> <strong>Status</strong>: Renewed <strong>Why</strong>: CBS reached a deal with series star Mark Harmon in early 2013, keeping the No. 1 show in America around for a Season 11.

  • "NCIS: LA"

    <strong>"NCIS: LA," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Viewers love their "NCIS," in any form. The ratings have been strong and the network is producing a backdoor spinoff pilot for this spinoff show. A full night of "NCIS" could be in CBS's future.

  • "Partners"

    <strong>"Partners," CBS</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: Low ratings and unfavorable reviews led to the <a href="http://www.huffingtonpost.com/2012/11/16/partners-canceled-cbs_n_2145832.html">early demise</a> of this CBS comedy.

  • "Person of Interest"

    <strong>"Person of Interest," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: The series has developed a nice-sized audience, bigger than its first season.

  • "Rules of Engagement"

    <strong>"Rules of Engagement," CBS</strong> <strong>Status</strong>: Honestly, who knows <strong>Why</strong>: This comedy has been on the bubble since it premiered ... yet is now in its seventh season. It's too soon to look at the numbers for this season, but the show has been a midseason success for CBS in the past. However, series co-star <a href="http://insidetv.ew.com/2013/02/07/cbs-orders-comedy-pilot-starring-patrick-warburton/">Patrick Warburton is attached to star in a new pilot</a> ... for CBS.

  • "Survivor"

    <strong>"Survivor," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: A strong player for the last 13 years, "Survivor" will likely be back. But due to its <a href="http://www.huffingtonpost.com/2013/02/14/survivor-ratings-lowest-premiere-ever_n_2687591.html">most recent premiere ratings</a>, we might not see it during the fall season, though a midseason or summer return -- with some new gimmick -- is definitely in the cards for the reality series.

  • "Two and a Half Men"

    <strong>"Two and a Half Men," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: CBS wants another season of this bawdy hit, it's just a matter of getting its stars to sign back on.

  • "Undercover Boss"

    <strong>"Undercover Boss," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: The show is enjoying life in syndication and its Season 4 numbers are better than most of its third season.

  • "Unforgettable"

    <strong>"Unforgettable," CBS</strong> <strong>Status</strong>: Uncanceled <strong>Why</strong>: CBS canceled the Poppy Montgomery drama last season ... and then revived it! Season 2 premieres Sunday, July 28.

  • "Vegas"

    <strong>"Vegas," CBS</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: Despite star power, the series hasn't been a breakout hit in the ratings. CBS previously canceled "Unforgettable" (then uncanceled it) last season when it was doing about the same as "Vegas."

  • Source: http://www.huffingtonpost.com/2013/02/27/justified-major-death-little-impact-video_n_2771688.html

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    The Establishment's Obama Derangement Syndrome (talking-points-memo)

    Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

    Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/287827396?client_source=feed&format=rss

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    Researchers explore PKC role in lung disease

    Tuesday, February 26, 2013
    A JGP study examines the role of PKC in airway smooth muscle contraction and raises the possibility that this enzyme could be a therapeutic target for treating asthma, COPD, and other lung diseases. The diagram shown summarizes the pathways regulating airway smooth muscle contraction. Credit: Dixon, R.E., and L.F. Santana. 2013. J. Gen. Physiol. appear in The Journal of General Physiology, provide new insight into the mechanisms involved in regulating luminal diameter of small airways and reveal PKC as a potential target for drug therapies.

    The researchers used phase-contrast video microscopy, confocal microscopy, Western blot analysis, and pharmacological activators and inhibitors to investigate the role of PKC in airway SMC contraction in mouse lung slices. Their results suggest that activation of PKC in small airways promotes an influx of calcium into SMC and subsequent intracellular release of calcium ions to generate low frequency SMC twitching. PKC activation also induces a strong calcium ion sensitization of contraction, eliciting a stronger contractile response to stimuli that increase free intracellular calcium. Consequently, PKC activation downstream of various molecules, such as thrombin, that are present in the airways in conjunction with inflammatory lung diseases, could sensitize the airway SMCs to contractile stimuli and contribute to the airway hyper responsiveness that is characteristic of asthma and COPD.

    ###

    Rockefeller University Press: http://www.rupress.org/

    Thanks to Rockefeller University Press for this article.

    This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

    This press release has been viewed 35 time(s).

    Source: http://www.labspaces.net/127020/Researchers_explore_PKC_role_in_lung_disease_

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    Why Was Jennifer Lawrence Wearing 5 1/2 Inch Heels? (PHOTOS, VIDEO)

    When Jennifer Lawrence won the most coveted award for any actress in Hollywood on Sunday, she was almost literally upstaged by the famous fall she took as she ascended the steps to accept it. The culprit? The big, beautiful Dior Haute Couture gown, in part, with a skirt so voluminous it practically covered Bradley Cooper's mother.

    But you know what certainly didn't help? The these 5 1/2-inch Brian Atwood heels she was wearing underneath. Why, God (or JLaw), why??

    atwood heels

    The 5'9" star of "Silver Linings Playbook" hardly needs any vertical assistance. And there's no denying that those shoes are works of art--but worn under that gown they're like the proverbial tree falling in the forest. Who can even appreciate them?

    Our industry likes to say beauty is pain, but what was beautiful about Lena Dunham's 6-inch-heel hobble at the Golden Globes? Or Jennifer Lawrence falling in front of 40 million Americans?

    In our opinion, every actress should take a page from Sally Field's, um, playbook and sport sneakers (or at least some flats) under those big ole gowns. Who's with us?

    PHOTOS:

    jennifer lawrence trips oscars

    jennifer lawrence trips oscars

    Watch the clip of the fall below:

    See more of Jennifer's style!

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    • February 2007

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    Want more? Be sure to check out HuffPost Style on Twitter, Facebook, Tumblr, Pinterest and Instagram at @HuffPostStyle.
    --
    Do you have a style story idea or tip? Email us at stylesubmissions@huffingtonpost.com. (PR pitches sent to this address will be ignored.)

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    Source: http://www.huffingtonpost.com/2013/02/25/jennifer-lawrence-brian-atwood-oscars_n_2761174.html

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    Tuesday 26 February 2013

    Alexandria & Cairo, 2 Day Tour


    Highlights:

    Visit the great Pyramids of Giza Plateau.
    Watch the Majestic Sphinx.
    Explore the halls of the Valley temple.
    Enjoy watching the collections of the Egyptian museum.
    Expert the mighty of the young pharaoh Tutankhamen
    and his collection of pure gold.

    Visit one of the most important Roman Tombs
    Catacombs

    Visit one of the most strong defensive fortress
    Qaitbay Citadel

    Discover biblothica of Alexandria

    Itinerary:

    First Day: Pyramids Tour /

    Egyptian Museum

    You will be Picked-up by your Tour Guide, holding a sign youre your name by the Cruise exit at Port Said. Transportation will take about 3 hours by an air-conditioned vehicle according to your need to get some rest you will have one stop in the way.

    Begin your day with a visit to the Pyramids of Cheops, Chephren and Mykerinus. Then you can explore the area of the

    Sphinx , which includes the statue of the Sphinx, the largest statue in the world which popularized awe and fear in the hearts of the visitors in the ancient times and nowadays and the valley temple, both of them belong to king Chephren pyramid complex. Secondly in this area you can discover the great feeling of walking in the ancient hall and corridors of the Valley Temple.

    Continue your excursion to the the Egyptian Museum which contains the most important artifacts from different eras of Ancient Egypt. The museum displays a rare collection of 5000 years of royal ornaments like this collection of the of the young Pharaoh

    Tutankhamen which contains his famous golden mask, Jewelry Sarcophagus and a lot other items. You can also enter the Mummy room extra ticket which houses 11mummified pharaoh. The museum collections include over 120,000 items and considered to be the most precious collection of Egyptian art in the whole world.

    Take your lunch at local restaurant.then you will be accompanied to your hotel.

    Then you will have the Choice to either have dinner aboard a Nile cruise for two hours on the Nile. Or watch Sound & Light show at the Giza Pyramids area . Overnight Cairo.

    Second Day: Alexandria Tour

    Enjoy your breakfast at the hotel, then youll travel with your private guide by air-conditioned modern vehicle to Alexandria where you will visit Catacomb which named by that name that its planning like the Christian catacomb in Rome, and dates back between (1st: 4th ) A.D centuries , gathered between the Ancient Egyptian art and the Greek-Roman art.

    Continue to

    Qaitbay citadel which was established by Sultan Al-Ashraf Saif El-Din Qaitbay at the far west side of Alexandria at the end of Pharos island on the exact site of the famous Ptolemaic Light house of Alexandria, as it was a very important defensive stronghold along the Mediterranean coast.

    Discover Alexandria library from inside. Then have your lunch through the tour. After that you will head back to the cruise for your final departure.

    Accommodation:
    Mena House Oberoi, Cairo

    Whats included:

    Pick up services from your hotel and return
    Assistance of our personal during your tours
    All transfers by air-conditioned deluxe vehicle
    Service of professional Egyptologist tour guide
    Entrance fees to the sights in Cairo & Alexandria
    Lunch during tours in Cairo at quality restaurant
    Shopping tours through Cairo famous Bazaars
    1 bottled water during tours in Cairo
    Accommodation in Cairo at 5* hotel with breakfast
    All services charges and taxes included in your price included

    Whats Excluded:

    Any optional tours mentioned in the itinerary
    Drinks and any personal expenses
    Entrance fees to special archaeological sites like (Mummies room at the Egyptian Museum- Inside one of the Pyramids ).
    Tipping Kitty

    Source: http://www.articlesnatch.com/Article/Alexandria---Cairo--2-Day-Tour/4457053

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    Deal of the Day ? 10.1? Lenovo IdeaTab S2110 32GB Android 4.0 tablet with Keyboard Dock

    Monday’s LogicBUY Deal is the customizable?10.1″ Lenovo IdeaTab S2110 Android 4.0 tablet with bundled Keyboard Dock (2258E5U)?for $349. ?Standard features: Qualcomm 1.5GHz dual-core and 1GB of LPDDR2 RAM 32GB memory IPS screen in HD resolution Front and rear camera Dual speakers with SRS TruMedia Keyboard dock has a?built-in battery with 18-20 hours runtime, 2 USB [...]

    Source: http://the-gadgeteer.com/2013/02/25/deal-of-the-day-10-1-lenovo-ideatab-s2110-32gb-android-4-0-tablet-with-keyboard-dock-2/

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    Ask Environmental Protection Agency to Label Hazardous Plast ...


    Judy C. (93)
    Monday February 25, 2013, 5:27 am
    Signed. Thanks Cher.

    Why is this inappropriate?